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Lifestyle Intervention vs. Usual Care

Context

The ornish-lifestyle-heart-trial randomized patients with coronary atherosclerosis into an intensive lifestyle modification group versus a usual-care control group.

Dimensions of Comparison

Dimension Intensive Lifestyle Intervention Usual Care
Diet very-low-fat-vegetarian-diet (~10% fat) Standard American Heart Association diet advice
Exercise Moderate aerobic exercise No structured requirement
Stress Management Yoga, meditation, group support None
Plaque Change Stenosis decreased (regression) Stenosis progressed
Angina Reduction 72% decrease in frequency Minimal change
MACE Risk Significantly lower 2.47x higher risk ratio

Verdict

Intensive, multi-component lifestyle-modification can induce measurable plaque-regression and reduce clinical cardiac events compared to standard medical advice alone.